SIGNIFICANCE OF MICRO-VESSELS WITHIN ATHEROSCLEROTIC CORONARY PLAQUES: A STUDY WITH MULTIPLE INTRAVASCULAR IMAGING MODALITIES

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging.

BACKGROUND Development and validation of novel imaging modalities to assess the composition of human atherosclerotic plaques will improve the understanding of atheroma evolution and could facilitate evaluation of therapeutic strategies for plaque modification. Surface MRI can characterize tissue content of carotid but not deeper arteries. This study evaluated the usefulness of intravascular MRI...

Detection of Atherosclerotic Coronary Plaques by Fluorescence Lifetime Imaging

Molecular Imaging of Atherosclerotic Coronary Plaques by Fluorescent Angioscopy

It is generally believed that the coronary plaques with lipid-laden thin fibrous cap and a large lipid core beneath are vulnerable and imaging methods such as intravascular ultrasonography1, optical coherence tomography2, and angioscopy3-5 are clinically employed to detect this type of plaques. However, the coronary plaques that have a thin cap composed of tight calcium layers are frequently ob...

Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound.

OBJECTIVES The aim of this study was to evaluate the feasibility and the ability of intravascular optical coherence tomography (OCT) to visualize the components of coronary plaques in living patients. BACKGROUND Disruption of a vulnerable coronary plaque with subsequent thrombosis is currently recognized as the primary mechanism for acute myocardial infarction. Although such plaques are consi...

Prevalence of Atherosclerotic Plaques in Autopsy Cases with Noncardiac Death

  Background and Objective: Ischemic heart disease (IHD) following atherosclerosis is the most common cause of cardiac deaths world wide. We aimed to investigate the pathologic features of atherosclerosis in non cardiac death cases to have an estimate of atherosclerosis prevalence in Mashad (North east of Iran). Patients and Methods : This descriptive (cross sectional) study was done, during ...